{"id":13360,"date":"2020-03-28T16:12:45","date_gmt":"2020-03-28T21:12:45","guid":{"rendered":"https:\/\/guleben.com\/?p=13360"},"modified":"2026-04-30T01:41:05","modified_gmt":"2026-04-30T05:41:05","slug":"simbioticos","status":"publish","type":"post","link":"https:\/\/guleben.com\/en\/blog\/general-public\/synbiotics\/","title":{"rendered":"SYMBIOTICS, THE PERFECT COMBINATION"},"content":{"rendered":"<div data-elementor-type=\"wp-post\" data-elementor-id=\"13360\" class=\"elementor elementor-13360\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-277420d elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"277420d\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-6fff4ce\" data-id=\"6fff4ce\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-49030df elementor-widget elementor-widget-text-editor\" data-id=\"49030df\" data-element_type=\"widget\" data-e-type=\"widget\" data-no-translation=\"\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t<style>.elementor-element-49030df{display:none !important}<\/style>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1fb49f4 elementor-widget elementor-widget-text-editor\" data-id=\"1fb49f4\" data-element_type=\"widget\" data-e-type=\"widget\" data-no-translation=\"\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p data-start=\"5886\" data-end=\"6170\">In nutraceutical science, the term synbiotics refers to the combination of probiotics and prebiotics. This mixture allows the development of integrated products that deliver the benefits of probiotic bacteria while ensuring their survival in the gut by providing an optimal substrate.<\/p><p data-start=\"6172\" data-end=\"6336\">The World Health Organization and FAO defined probiotics as \u201clive microorganisms which, when administered in adequate amounts, confer a health benefit on the host\u201d.<\/p><p data-start=\"6338\" data-end=\"6600\">Later, in 2013, the International Scientific Association for Probiotics and Prebiotics (ISAPP) reaffirmed this definition. In 2016, ISAPP further defined synbiotics as \u201ca substrate that is selectively utilized by host microorganisms conferring a health benefit\u201d.<\/p><h2 data-section-id=\"1hefm91\" data-start=\"6602\" data-end=\"6627\">Benefits of synbiotics<\/h2><p data-start=\"6629\" data-end=\"6739\">Synbiotics combine the effects of probiotics and prebiotics, making it essential to understand each component.<\/p><h3 data-section-id=\"1r9h827\" data-start=\"6741\" data-end=\"6767\">Benefits of probiotics<\/h3><p data-start=\"6769\" data-end=\"6901\">Probiotics are commonly found in dietary supplements and functional foods. Their effects depend on the strain and condition treated.<\/p><p data-start=\"6903\" data-end=\"6939\">Evidence-supported benefits include:<\/p><ul data-start=\"6941\" data-end=\"7388\"><li data-section-id=\"5pyuel\" data-start=\"6941\" data-end=\"6988\">Reduction of antibiotic-associated diarrhea<\/li><li data-section-id=\"198wuyn\" data-start=\"6989\" data-end=\"7052\">Improvement of digestive symptoms such as bloating and pain<\/li><li data-section-id=\"pwrhyg\" data-start=\"7053\" data-end=\"7082\">Reduction of infant colic<\/li><li data-section-id=\"16gg9h2\" data-start=\"7083\" data-end=\"7130\">Improvement of lactose intolerance symptoms<\/li><li data-section-id=\"111cpx5\" data-start=\"7131\" data-end=\"7173\">Reduction of eczema in atopic children<\/li><li data-section-id=\"101jvxs\" data-start=\"7174\" data-end=\"7216\">Treatment of acute infectious diarrhea<\/li><li data-section-id=\"2yukkj\" data-start=\"7217\" data-end=\"7257\">Management of C. difficile infection<\/li><li data-section-id=\"5ezki6\" data-start=\"7258\" data-end=\"7297\">Reduction of respiratory infections<\/li><li data-section-id=\"ycv4j8\" data-start=\"7298\" data-end=\"7337\">Prevention of intestinal infections<\/li><li data-section-id=\"iu3r6l\" data-start=\"7338\" data-end=\"7388\">Reduction of genitourinary infections in women<\/li><\/ul><h3 data-section-id=\"2h3nb9\" data-start=\"7390\" data-end=\"7416\">Benefits of prebiotics<\/h3><p data-start=\"7418\" data-end=\"7516\">Common prebiotics include inulin, fructooligosaccharides (FOS), and galactooligosaccharides (GOS).<\/p><p data-start=\"7518\" data-end=\"7540\">Their effects include:<\/p><ul data-start=\"7542\" data-end=\"7753\"><li data-section-id=\"1mlzdhz\" data-start=\"7542\" data-end=\"7591\">Production of short-chain fatty acids (SCFAs)<\/li><li data-section-id=\"107j6go\" data-start=\"7592\" data-end=\"7637\">Growth stimulation of beneficial bacteria<\/li><li data-section-id=\"15shepn\" data-start=\"7638\" data-end=\"7668\">Reduction of intestinal pH<\/li><li data-section-id=\"1s7nuvb\" data-start=\"7669\" data-end=\"7700\">Improved mineral absorption<\/li><li data-section-id=\"1t098nq\" data-start=\"7701\" data-end=\"7753\">Increased stool bulk and improved bowel movement<\/li><\/ul><p data-start=\"7755\" data-end=\"7775\">Additional benefits:<\/p><ul data-start=\"7777\" data-end=\"8062\"><li data-section-id=\"zb43x\" data-start=\"7777\" data-end=\"7805\">Metabolic health support<\/li><li data-section-id=\"1nul0fj\" data-start=\"7806\" data-end=\"7827\">Increased satiety<\/li><li data-section-id=\"15lau40\" data-start=\"7828\" data-end=\"7868\">Neurochemical stimulation in the gut<\/li><li data-section-id=\"pt93ct\" data-start=\"7869\" data-end=\"7892\">Bone health support<\/li><li data-section-id=\"15yd6jz\" data-start=\"7893\" data-end=\"7917\">Skin health benefits<\/li><li data-section-id=\"xi6oee\" data-start=\"7918\" data-end=\"7968\">Allergy and inflammatory bowel disease support<\/li><li data-section-id=\"15i9jkb\" data-start=\"7969\" data-end=\"8003\">Traveler\u2019s diarrhea prevention<\/li><li data-section-id=\"nehw1k\" data-start=\"8004\" data-end=\"8027\">Constipation relief<\/li><li data-section-id=\"186q3a4\" data-start=\"8028\" data-end=\"8062\">Immune support in older adults<\/li><\/ul><h2 data-section-id=\"zx68uj\" data-start=\"8064\" data-end=\"8095\">Effects on the immune system<\/h2><p data-start=\"8097\" data-end=\"8198\">About 70% of the immune system resides in the gut, making microbiota essential for immune regulation.<\/p><p data-start=\"8200\" data-end=\"8218\">Synbiotics act by:<\/p><ul data-start=\"8220\" data-end=\"8392\"><li data-section-id=\"vpjvzs\" data-start=\"8220\" data-end=\"8248\">Increasing IgA secretion<\/li><li data-section-id=\"1xo43by\" data-start=\"8249\" data-end=\"8281\">Enhancing regulatory T cells<\/li><li data-section-id=\"sgapjt\" data-start=\"8282\" data-end=\"8321\">Promoting dendritic cell maturation<\/li><li data-section-id=\"1vwo4qs\" data-start=\"8322\" data-end=\"8362\">Inducing anti-inflammatory cytokines<\/li><li data-section-id=\"1erg3mt\" data-start=\"8363\" data-end=\"8392\">Regulating immune balance<\/li><\/ul><p data-start=\"8394\" data-end=\"8452\">These mechanisms support both local and systemic immunity.<\/p><h2 data-section-id=\"keex1y\" data-start=\"8454\" data-end=\"8483\">Microbiota and development<\/h2><p data-start=\"8485\" data-end=\"8529\">Gut microbiota development is influenced by:<\/p><ul data-start=\"8531\" data-end=\"8596\"><li data-section-id=\"zlmta1\" data-start=\"8531\" data-end=\"8548\">Breastfeeding<\/li><li data-section-id=\"m51awy\" data-start=\"8549\" data-end=\"8572\">Dietary transitions<\/li><li data-section-id=\"1gmfv2r\" data-start=\"8573\" data-end=\"8596\">Antibiotic exposure<\/li><\/ul><p data-start=\"8598\" data-end=\"8688\">Antibiotics can disrupt microbial balance, affecting both harmful and beneficial bacteria.<\/p><h2 data-section-id=\"u6ysv7\" data-start=\"8690\" data-end=\"8711\">Synbiotic products<\/h2><p data-start=\"8713\" data-end=\"8860\">Synbiotics are typically formulated as functional foods or dietary supplements combining prebiotics and probiotics tailored to specific conditions.<\/p><h2 data-section-id=\"1n1muep\" data-start=\"8862\" data-end=\"8894\">Key factors for effectiveness<\/h2><p data-start=\"8896\" data-end=\"8921\">Effectiveness depends on:<\/p><ul data-start=\"8923\" data-end=\"9021\"><li data-section-id=\"11atp38\" data-start=\"8923\" data-end=\"8944\">Type of prebiotic<\/li><li data-section-id=\"1e6fjt8\" data-start=\"8945\" data-end=\"8975\">Probiotic strain selection<\/li><li data-section-id=\"1xrzwav\" data-start=\"8976\" data-end=\"8995\">Adequate dosage<\/li><li data-section-id=\"1l8ugbk\" data-start=\"8996\" data-end=\"9021\">Scientific validation<\/li><\/ul><p data-start=\"9023\" data-end=\"9122\">Poor results are often due to incorrect strain selection, lack of evidence, or insufficient dosage.<\/p><h2 data-section-id=\"8dtpi\" data-start=\"9124\" data-end=\"9137\">Conclusion<\/h2><p data-start=\"9139\" data-end=\"9264\">Synbiotics represent an advanced approach in nutraceuticals by combining probiotics and prebiotics into a single formulation.<\/p><p data-start=\"9266\" data-end=\"9423\" data-is-last-node=\"\" data-is-only-node=\"\">Their success relies on scientific formulation, appropriate strain selection, and proper dosing, ensuring real benefits in disease prevention and management.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>La combinaci\u00f3n de prebi\u00f3ticos con Probi\u00f3ticos se ha definido como simbi\u00f3tico, siendo su mayor beneficio el aumento de la viabilidad e implantacion de los microorganismos vivos en el tracto gastro-intestinal (TGI). (world Gastroenterology Organitation , 2017)<\/p>","protected":false},"author":3,"featured_media":23689,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5],"tags":[3,4,6],"class_list":["post-13360","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-publico-general","tag-prebioticos","tag-probioticos","tag-simbioticos"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Simbi\u00f3ticos la combinaci\u00f3n perfecta para mejorar tu salud y la de tu familia<\/title>\n<meta name=\"description\" content=\"Los simbi\u00f3ticos son la combinaci\u00f3n de prebi\u00f3ticos y prob\u00edoticos, esta asociaci\u00f3n genera efectos positivos demostrados en tu salud\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" 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